EGF-00214 Green

OC(CNCc1ccccc1F)COCc1cccc(Cl)c1
0.683
Platform Score
2D Structure
EGF-00214
C17H19ClFNO2 | Exact mass: 323.1088
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
42
TPSA
324
MW
2
HBD
3.1
SlogP
Display Controls
Rotate: drag | Zoom: scroll | Pan: right-drag | Double-click: center Loading...
EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight323.80 Da
TPSA41.5 A^2
HBD2
HBA3
SlogP3.15
Fsp30.294
Rotatable Bonds8
Rings2 (2 aromatic)
QED0.784
SA Score2.40 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC17H19ClFNO2
Exact Mass323.1088
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes