EGF-00248 Green

OCCC1CN(Cc2cccc(F)c2F)CCN1Cc1cccnc1
0.677
Platform Score
2D Structure
EGF-00248
C19H23F2N3O | Exact mass: 347.1809
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
40
TPSA
347
MW
1
HBD
2.4
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight347.40 Da
TPSA39.6 A^2
HBD1
HBA4
SlogP2.43
Fsp30.421
Rotatable Bonds6
Rings3 (2 aromatic)
QED0.871
SA Score2.74 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC19H23F2N3O
Exact Mass347.1809
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes