EGF-00654 Green

O=S(=O)(Nc1cccc(F)c1F)c1nnc(Cc2cccnc2)s1
0.581
Platform Score
2D Structure
EGF-00654
C14H10F2N4O2S2 | Exact mass: 368.0213
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
85
TPSA
368
MW
1
HBD
2.6
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight368.40 Da
TPSA84.8 A^2
HBD1
HBA6
SlogP2.60
Fsp30.071
Rotatable Bonds5
Rings3 (3 aromatic)
QED0.748
SA Score2.56 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC14H10F2N4O2S2
Exact Mass368.0213
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes