EGF-00742 Green

CN(C)c1ncnc2c1CCN(S(=O)(=O)c1ccccc1)C2
0.581
Platform Score
2D Structure
EGF-00742
C15H18N4O2S | Exact mass: 318.115
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
66
TPSA
318
MW
0
HBD
1.3
SlogP
Display Controls
Rotate: drag | Zoom: scroll | Pan: right-drag | Double-click: center Loading...
EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight318.40 Da
TPSA66.4 A^2
HBD0
HBA5
SlogP1.29
Fsp30.333
Rotatable Bonds3
Rings3 (2 aromatic)
QED0.853
SA Score2.36 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC15H18N4O2S
Exact Mass318.115
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes