EGF-00826 Green

Clc1ccc(N2CCN(Cc3ccccc3)CC2)cc1Cl
0.642
Platform Score
2D Structure
EGF-00826
C17H18Cl2N2 | Exact mass: 320.0847
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
6
TPSA
321
MW
0
HBD
4.3
SlogP
Display Controls
Rotate: drag | Zoom: scroll | Pan: right-drag | Double-click: center Loading...
EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight321.30 Da
TPSA6.5 A^2
HBD0
HBA2
SlogP4.32
Fsp30.294
Rotatable Bonds3
Rings3 (2 aromatic)
QED0.831
SA Score1.62 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC17H18Cl2N2
Exact Mass320.0847
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes