EGF-00940 Green

O=C(Nc1cnn(Cc2ccccc2Cl)c1)C1CCCN1
0.604
Platform Score
2D Structure
EGF-00940
C15H17ClN4O | Exact mass: 304.1091
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
59
TPSA
305
MW
2
HBD
2.3
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight304.80 Da
TPSA59.0 A^2
HBD2
HBA4
SlogP2.28
Fsp30.333
Rotatable Bonds4
Rings3 (2 aromatic)
QED0.911
SA Score2.63 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC15H17ClN4O
Exact Mass304.1091
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes