EGF-01150 Green

Clc1ccc(N2CCN(c3ncccc3Cl)CC2)cc1Cl
0.625
Platform Score
2D Structure
EGF-01150
C15H14Cl3N3 | Exact mass: 341.0253
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
1
Hinge Binder
19
TPSA
343
MW
0
HBD
4.4
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight342.70 Da
TPSA19.4 A^2
HBD0
HBA3
SlogP4.37
Fsp30.267
Rotatable Bonds2
Rings3 (2 aromatic)
QED0.808
SA Score1.93 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC15H14Cl3N3
Exact Mass341.0253
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder 4-Aminoquinazoline Hinge
InChIKey-
Filter PassYes