EGF-01208 Yellow

COCCN1CCOC2(COCCN(c3ccccn3)C2)C1
0.537
Platform Score
2D Structure
EGF-01208
C16H25N3O3 | Exact mass: 307.1896
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
1
Hinge Binder
47
TPSA
307
MW
0
HBD
0.6
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight307.40 Da
TPSA47.1 A^2
HBD0
HBA6
SlogP0.64
Fsp30.688
Rotatable Bonds4
Rings3 (1 aromatic)
QED0.813
SA Score3.55 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC16H25N3O3
Exact Mass307.1896
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder 4-Aminoquinazoline Hinge
InChIKey-
Filter PassYes