EGF-01341 Yellow

COC1COC2CN(C(=O)c3ccoc3)CC12COCc1ccccc1
0.530
Platform Score
2D Structure
EGF-01341
C20H23NO5 | Exact mass: 357.1576
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
61
TPSA
357
MW
0
HBD
2.4
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight357.40 Da
TPSA61.1 A^2
HBD0
HBA5
SlogP2.35
Fsp30.450
Rotatable Bonds6
Rings4 (2 aromatic)
QED0.794
SA Score3.92 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC20H23NO5
Exact Mass357.1576
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes