EGF-01488 Yellow

CS(=O)(=O)N(CC(=O)NCCSCc1ccccc1)c1ccc(Cl)cc1
0.548
Platform Score
2D Structure
EGF-01488
C18H21ClN2O3S2 | Exact mass: 412.0682
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
66
TPSA
413
MW
1
HBD
3.2
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight413.00 Da
TPSA66.5 A^2
HBD1
HBA4
SlogP3.16
Fsp30.278
Rotatable Bonds9
Rings2 (2 aromatic)
QED0.642
SA Score2.09 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC18H21ClN2O3S2
Exact Mass412.0682
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes