EGF-01565 Green

Fc1ccc(Oc2cccc3nc(N4CCNCC4)cnc23)c(F)c1
0.581
Platform Score
2D Structure
EGF-01565
C18H16F2N4O | Exact mass: 342.1292
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
50
TPSA
342
MW
1
HBD
3.1
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight342.30 Da
TPSA50.3 A^2
HBD1
HBA5
SlogP3.11
Fsp30.222
Rotatable Bonds3
Rings4 (3 aromatic)
QED0.793
SA Score2.38 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC18H16F2N4O
Exact Mass342.1292
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes