EGF-01607 Green

CCOC(=O)c1c(NC(=O)c2ccccc2F)sc(C(N)=O)c1C
0.553
Platform Score
2D Structure
EGF-01607
C16H15FN2O4S | Exact mass: 350.0737
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
98
TPSA
350
MW
2
HBD
2.7
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight350.40 Da
TPSA98.5 A^2
HBD2
HBA5
SlogP2.72
Fsp30.188
Rotatable Bonds5
Rings2 (2 aromatic)
QED0.810
SA Score2.05 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC16H15FN2O4S
Exact Mass350.0737
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes