EGF-01612 Yellow

CN(CCNC(=O)c1cc(Cl)cc(Cl)c1)CCN(C(N)=O)c1ccccc1
0.541
Platform Score
2D Structure
EGF-01612
C19H22Cl2N4O2 | Exact mass: 408.112
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
79
TPSA
409
MW
2
HBD
3.2
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight409.30 Da
TPSA78.7 A^2
HBD2
HBA3
SlogP3.24
Fsp30.263
Rotatable Bonds8
Rings2 (2 aromatic)
QED0.703
SA Score2.29 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC19H22Cl2N4O2
Exact Mass408.112
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes