EGF-01688 Green

COc1ccc(Br)cc1CNC(=O)Nc1ccccc1
0.600
Platform Score
2D Structure
EGF-01688
C15H15BrN2O2 | Exact mass: 334.0317
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
50
TPSA
335
MW
2
HBD
3.8
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight335.20 Da
TPSA50.4 A^2
HBD2
HBA2
SlogP3.78
Fsp30.133
Rotatable Bonds4
Rings2 (2 aromatic)
QED0.893
SA Score1.63 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC15H15BrN2O2
Exact Mass334.0317
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes