EGF-01705 Yellow

O=C(N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)n1cccn1
0.532
Platform Score
2D Structure
EGF-01705
C14H15ClN4O3S | Exact mass: 354.0553
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
76
TPSA
355
MW
0
HBD
1.5
SlogP
Display Controls
Rotate: drag | Zoom: scroll | Pan: right-drag | Double-click: center Loading...
EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight354.80 Da
TPSA75.5 A^2
HBD0
HBA5
SlogP1.51
Fsp30.286
Rotatable Bonds2
Rings3 (2 aromatic)
QED0.819
SA Score2.27 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC14H15ClN4O3S
Exact Mass354.0553
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes