EGF-01846 Yellow

N=c1ncn(Cc2ccccc2OC(F)(F)F)c2cn[nH]c12
0.517
Platform Score
2D Structure
EGF-01846
C13H10F3N5O | Exact mass: 309.0837
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
80
TPSA
309
MW
2
HBD
2.2
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight309.30 Da
TPSA79.6 A^2
HBD2
HBA5
SlogP2.19
Fsp30.154
Rotatable Bonds3
Rings3 (3 aromatic)
QED0.778
SA Score2.98 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC13H10F3N5O
Exact Mass309.0837
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes