EGF-01907 Yellow

O=C(Nc1ccccc1N1CCOCC1)C1CCN(S(=O)(=O)c2cccs2)CC1
0.546
Platform Score
2D Structure
EGF-01907
C20H25N3O4S2 | Exact mass: 435.1286
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
79
TPSA
436
MW
1
HBD
2.6
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight435.60 Da
TPSA79.0 A^2
HBD1
HBA6
SlogP2.62
Fsp30.450
Rotatable Bonds5
Rings4 (2 aromatic)
QED0.781
SA Score2.20 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC20H25N3O4S2
Exact Mass435.1286
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes