EGF-01938 Green

O=C(Nc1cccc(F)c1F)N1CCN(S(=O)(=O)c2cccs2)CC1
0.571
Platform Score
2D Structure
EGF-01938
C15H15F2N3O3S2 | Exact mass: 387.0523
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
70
TPSA
387
MW
1
HBD
2.6
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight387.40 Da
TPSA69.7 A^2
HBD1
HBA4
SlogP2.56
Fsp30.267
Rotatable Bonds3
Rings3 (2 aromatic)
QED0.880
SA Score2.19 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC15H15F2N3O3S2
Exact Mass387.0523
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes