EGF-02144 Green

Cc1cc(C)n(C2CN(CC(=O)N(C)c3ncccc3C)C2)n1
0.560
Platform Score
2D Structure
EGF-02144
C17H23N5O | Exact mass: 313.1903
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
1
Hinge Binder
54
TPSA
313
MW
0
HBD
1.7
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight313.40 Da
TPSA54.3 A^2
HBD0
HBA5
SlogP1.72
Fsp30.471
Rotatable Bonds4
Rings3 (2 aromatic)
QED0.862
SA Score2.70 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC17H23N5O
Exact Mass313.1903
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder 4-Aminoquinazoline Hinge
InChIKey-
Filter PassYes