EGF-02204 Yellow

O=C(CNS(=O)(=O)Cc1ccc(Cl)cc1Cl)NC1CCCCC1
0.549
Platform Score
2D Structure
EGF-02204
C15H20Cl2N2O3S | Exact mass: 378.0572
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
75
TPSA
379
MW
2
HBD
2.9
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight379.30 Da
TPSA75.3 A^2
HBD2
HBA3
SlogP2.86
Fsp30.533
Rotatable Bonds6
Rings2 (1 aromatic)
QED0.798
SA Score2.19 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC15H20Cl2N2O3S
Exact Mass378.0572
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes