EGF-02317 Yellow

CCC(NC(=O)OCc1ccccc1)c1cnccc1C(F)(F)F
0.534
Platform Score
2D Structure
EGF-02317
C17H17F3N2O2 | Exact mass: 338.1242
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
51
TPSA
338
MW
1
HBD
4.5
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight338.30 Da
TPSA51.2 A^2
HBD1
HBA3
SlogP4.48
Fsp30.294
Rotatable Bonds5
Rings2 (2 aromatic)
QED0.874
SA Score2.67 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC17H17F3N2O2
Exact Mass338.1242
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes