EGF-02345 Green

Fc1ccc(C(=S)NC2CCN(Cc3ccccc3)CC2)cc1
0.592
Platform Score
2D Structure
EGF-02345
C19H21FN2S | Exact mass: 328.1409
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
15
TPSA
328
MW
1
HBD
3.8
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight328.50 Da
TPSA15.3 A^2
HBD1
HBA2
SlogP3.76
Fsp30.316
Rotatable Bonds4
Rings3 (2 aromatic)
QED0.861
SA Score1.95 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC19H21FN2S
Exact Mass328.1409
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes