EGF-02441 Green

COc1ccccc1N1CCN(CC(C)Cc2ccon2)CC1
0.552
Platform Score
2D Structure
EGF-02441
C18H25N3O2 | Exact mass: 315.1947
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
42
TPSA
315
MW
0
HBD
2.7
SlogP
Display Controls
Rotate: drag | Zoom: scroll | Pan: right-drag | Double-click: center Loading...
EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight315.40 Da
TPSA41.7 A^2
HBD0
HBA5
SlogP2.68
Fsp30.500
Rotatable Bonds6
Rings3 (2 aromatic)
QED0.820
SA Score2.80 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC18H25N3O2
Exact Mass315.1947
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes