EGF-02610 Yellow

Fc1cnc(OC2CCCCCC2)[nH]c1=Nc1ccc(N2CCOCC2)cc1
0.519
Platform Score
2D Structure
EGF-02610
C21H27FN4O2 | Exact mass: 386.2118
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
63
TPSA
386
MW
1
HBD
3.7
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight386.50 Da
TPSA62.7 A^2
HBD1
HBA5
SlogP3.72
Fsp30.524
Rotatable Bonds4
Rings4 (2 aromatic)
QED0.814
SA Score2.92 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC21H27FN4O2
Exact Mass386.2118
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes