EGF-02969 Green

Cc1c(Cl)cccc1NC(=O)N1CCN(c2ccccn2)CC1
0.596
Platform Score
2D Structure
EGF-02969
C17H19ClN4O | Exact mass: 330.1247
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
1
Hinge Binder
48
TPSA
331
MW
1
HBD
3.4
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight330.80 Da
TPSA48.5 A^2
HBD1
HBA3
SlogP3.40
Fsp30.294
Rotatable Bonds2
Rings3 (2 aromatic)
QED0.918
SA Score1.92 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC17H19ClN4O
Exact Mass330.1247
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder 4-Aminoquinazoline Hinge
InChIKey-
Filter PassYes