EGF-03158 Green

N#Cc1cc(Cl)ccc1N1CCN(c2ccccc2F)CC1
0.559
Platform Score
2D Structure
EGF-03158
C17H15ClFN3 | Exact mass: 315.0939
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
30
TPSA
316
MW
0
HBD
3.7
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight315.80 Da
TPSA30.3 A^2
HBD0
HBA3
SlogP3.68
Fsp30.235
Rotatable Bonds2
Rings3 (2 aromatic)
QED0.847
SA Score1.96 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC17H15ClFN3
Exact Mass315.0939
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes