EGF-03489 Red

Oc1c2c(c(O)n1-c1ccc(Cl)c(C(F)(F)F)c1)C(c1ccncc1)N(c1ccccc1)O2
0.338
Platform Score
2D Structure
EGF-03489
C23H15ClF3N3O3 | Exact mass: 473.0754
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
71
TPSA
474
MW
2
HBD
5.9
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight473.80 Da
TPSA70.8 A^2
HBD2
HBA6
SlogP5.86
Fsp30.087
Rotatable Bonds3
Rings5 (4 aromatic)
QED0.390
SA Score3.45 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC23H15ClF3N3O3
Exact Mass473.0754
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes