EGF-03685 Red

COc1ccccc1NC(=O)Cn1c(=O)n(Cc2nncn2C)c(=O)c2cc(OC)c(OC)cc21
0.335
Platform Score
2D Structure
EGF-03685
C23H24N6O6 | Exact mass: 480.1757
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
132
TPSA
480
MW
1
HBD
1.0
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight480.50 Da
TPSA131.5 A^2
HBD1
HBA11
SlogP1.00
Fsp30.261
Rotatable Bonds8
Rings4 (4 aromatic)
QED0.395
SA Score2.51 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC23H24N6O6
Exact Mass480.1757
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes