EGF-04803 Red

Cc1ccc2onc(C3CC4CC5(C4)CN3CC(c3ccccc3)=NO5)c2c1
0.307
Platform Score
2D Structure
EGF-04803
C23H23N3O2 | Exact mass: 373.179
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
51
TPSA
374
MW
0
HBD
4.5
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight373.50 Da
TPSA50.9 A^2
HBD0
HBA5
SlogP4.47
Fsp30.391
Rotatable Bonds2
Rings7 (3 aromatic)
QED0.665
SA Score5.10 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC23H23N3O2
Exact Mass373.179
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes