EGF-04935 Red

Nc1c(C(=O)NC2c3ccccc3-c3ccccc32)noc1C(=O)c1ccc(Cl)cc1
0.293
Platform Score
2D Structure
EGF-04935
C24H16ClN3O3 | Exact mass: 429.088
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
98
TPSA
430
MW
2
HBD
4.6
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight429.90 Da
TPSA98.2 A^2
HBD2
HBA5
SlogP4.64
Fsp30.042
Rotatable Bonds4
Rings5 (4 aromatic)
QED0.460
SA Score2.50 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC24H16ClN3O3
Exact Mass429.088
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes