EGF-05165 Red

Cn1c(=O)c(=O)n(C)c2nc(-c3ccccc3)cc(-c3ccccc3)c2c1=O
0.352
Platform Score
2D Structure
EGF-05165
C22H17N3O3 | Exact mass: 371.127
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
74
TPSA
371
MW
0
HBD
2.3
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight371.40 Da
TPSA74.0 A^2
HBD0
HBA6
SlogP2.33
Fsp30.091
Rotatable Bonds2
Rings4 (4 aromatic)
QED0.507
SA Score2.19 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC22H17N3O3
Exact Mass371.127
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes