EGF-05189 Red

O=C1C(Oc2ccc(F)cc2)C(c2ccccc2)N1CC(O)n1ccnc1
0.362
Platform Score
2D Structure
EGF-05189
C20H18FN3O3 | Exact mass: 367.1332
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
68
TPSA
367
MW
1
HBD
2.5
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight367.40 Da
TPSA67.6 A^2
HBD1
HBA5
SlogP2.54
Fsp30.200
Rotatable Bonds6
Rings4 (3 aromatic)
QED0.680
SA Score3.56 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC20H18FN3O3
Exact Mass367.1332
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes