EGF-05258 Red

Cc1ncc([N+](=O)[O-])n1CCOC(C)(c1ccccc1)c1ccccn1
0.321
Platform Score
2D Structure
EGF-05258
C19H20N4O3 | Exact mass: 352.1535
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
83
TPSA
352
MW
0
HBD
3.5
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight352.40 Da
TPSA83.1 A^2
HBD0
HBA6
SlogP3.48
Fsp30.263
Rotatable Bonds7
Rings3 (3 aromatic)
QED0.480
SA Score3.14 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC19H20N4O3
Exact Mass352.1535
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes