EGF-05275 Red

COC(=O)c1ccc(Cl)c(NC(Cc2ccc(OCCc3nc(-c4ccccc4)oc3C)cc2)C(=O)O)c1
0.201
Platform Score
2D Structure
EGF-05275
C29H27ClN2O6 | Exact mass: 534.1558
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
111
TPSA
535
MW
2
HBD
5.8
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight535.00 Da
TPSA110.9 A^2
HBD2
HBA7
SlogP5.82
Fsp30.207
Rotatable Bonds11
Rings4 (4 aromatic)
QED0.232
SA Score2.83 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC29H27ClN2O6
Exact Mass534.1558
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes