EGF-05350 Red

COc1ccccc1-c1ccc(CC(C#N)NC(=O)C2NC3CCC2CC3)nc1
0.361
Platform Score
2D Structure
EGF-05350
C23H26N4O2 | Exact mass: 390.2056
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
87
TPSA
390
MW
2
HBD
2.8
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight390.50 Da
TPSA87.0 A^2
HBD2
HBA5
SlogP2.84
Fsp30.435
Rotatable Bonds6
Rings5 (2 aromatic)
QED0.792
SA Score4.26 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC23H26N4O2
Exact Mass390.2056
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes