EGF-05570 Red

O=C(c1cn(CCO)c2cc(N3CCOCC3)ccc12)c1nn(C2CCCOC2)c2ccccc12
0.311
Platform Score
2D Structure
EGF-05570
C27H30N4O4 | Exact mass: 474.2267
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
82
TPSA
475
MW
1
HBD
3.4
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight474.60 Da
TPSA81.8 A^2
HBD1
HBA8
SlogP3.40
Fsp30.407
Rotatable Bonds6
Rings6 (4 aromatic)
QED0.432
SA Score3.29 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC27H30N4O4
Exact Mass474.2267
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes