EGF-05666 Red

O=C(Nc1ccc(S(=O)(=O)N2CCCCCC2)cc1)c1cc(-c2cccnc2)nc2ccccc12
0.287
Platform Score
2D Structure
EGF-05666
C27H26N4O3S | Exact mass: 486.1726
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
92
TPSA
487
MW
1
HBD
5.1
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight486.60 Da
TPSA92.3 A^2
HBD1
HBA5
SlogP5.11
Fsp30.222
Rotatable Bonds5
Rings5 (4 aromatic)
QED0.423
SA Score2.16 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC27H26N4O3S
Exact Mass486.1726
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes