EGF-05718 Red

Cn1cc(CC(=O)Nc2ccc(S(=O)(=O)NCc3cccnc3)cc2)c2ccccc21
0.342
Platform Score
2D Structure
EGF-05718
C23H22N4O3S | Exact mass: 434.1413
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
93
TPSA
434
MW
2
HBD
3.2
SlogP
Display Controls
Rotate: drag | Zoom: scroll | Pan: right-drag | Double-click: center Loading...
EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight434.50 Da
TPSA93.1 A^2
HBD2
HBA5
SlogP3.23
Fsp30.130
Rotatable Bonds7
Rings4 (4 aromatic)
QED0.467
SA Score2.17 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC23H22N4O3S
Exact Mass434.1413
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes