EGF-05760 Red

CC(NC(=O)c1ccc(CNC(=O)c2cccc(F)c2)cc1)c1ccccc1
0.384
Platform Score
2D Structure
EGF-05760
C23H21FN2O2 | Exact mass: 376.1587
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
58
TPSA
376
MW
2
HBD
4.2
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight376.40 Da
TPSA58.2 A^2
HBD2
HBA2
SlogP4.25
Fsp30.130
Rotatable Bonds6
Rings3 (3 aromatic)
QED0.676
SA Score2.13 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC23H21FN2O2
Exact Mass376.1587
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes
Retrosynthetic Analysis

Retrosynthetic analysis not yet run for this compound.

About

Retrosynthetic analysis decomposes the target molecule into purchasable building blocks using learned reaction templates.

A feasible route means the molecule can theoretically be synthesized from commercially available starting materials.

Min steps indicates the shortest synthesis route found.