EGF-05766 Red

Cn1cnnc1C1CN(Cc2nc(Cc3ccccc3F)no2)CCO1
0.336
Platform Score
2D Structure
EGF-05766
C17H19FN6O2 | Exact mass: 358.1554
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
82
TPSA
358
MW
0
HBD
1.5
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight358.40 Da
TPSA82.1 A^2
HBD0
HBA8
SlogP1.50
Fsp30.412
Rotatable Bonds5
Rings4 (3 aromatic)
QED0.683
SA Score3.20 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC17H19FN6O2
Exact Mass358.1554
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes