EGF-06091 Red

Cc1cc(CN2CCC(O)C2)ccc1C(=O)Cn1ncc(OCc2ccccc2)cc1=O
0.343
Platform Score
2D Structure
EGF-06091
C25H27N3O4 | Exact mass: 433.2002
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
85
TPSA
434
MW
1
HBD
2.6
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight433.50 Da
TPSA84.7 A^2
HBD1
HBA7
SlogP2.58
Fsp30.320
Rotatable Bonds8
Rings4 (3 aromatic)
QED0.550
SA Score2.85 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC25H27N3O4
Exact Mass433.2002
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes