EGF-06185 Red

O=C(C1OC(=O)N(c2ccc(F)c(F)c2)C1c1ccccc1)N1CCCC1c1ccccc1
0.303
Platform Score
2D Structure
EGF-06185
C26H22F2N2O3 | Exact mass: 448.1598
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
50
TPSA
448
MW
0
HBD
5.4
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight448.50 Da
TPSA49.9 A^2
HBD0
HBA3
SlogP5.40
Fsp30.231
Rotatable Bonds4
Rings5 (3 aromatic)
QED0.537
SA Score3.36 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC26H22F2N2O3
Exact Mass448.1598
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes