EGF-06273 Red

N=C(N)NCCCC(NCc1ccc2ccccc2c1)C(=O)O
0.255
Platform Score
2D Structure
EGF-06273
C17H22N4O2 | Exact mass: 314.1743
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
111
TPSA
314
MW
5
HBD
1.6
SlogP
Display Controls
Rotate: drag | Zoom: scroll | Pan: right-drag | Double-click: center Loading...
EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight314.40 Da
TPSA111.2 A^2
HBD5
HBA3
SlogP1.65
Fsp30.294
Rotatable Bonds8
Rings2 (2 aromatic)
QED0.289
SA Score2.57 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC17H22N4O2
Exact Mass314.1743
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes