EGF-06281 Red

CC(=NNC(=O)CNN)c1ccc(NS(=O)(=O)c2ccccc2)cc1
0.241
Platform Score
2D Structure
EGF-06281
C16H19N5O3S | Exact mass: 361.1209
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
126
TPSA
361
MW
4
HBD
0.8
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight361.40 Da
TPSA125.7 A^2
HBD4
HBA6
SlogP0.79
Fsp30.125
Rotatable Bonds7
Rings2 (2 aromatic)
QED0.330
SA Score2.21 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC16H19N5O3S
Exact Mass361.1209
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes