EGF-06285 Red

COc1ccc(C=NNC(=O)C(=O)Nc2cccc3ccccc23)cc1OC(=O)c1ccccc1
0.245
Platform Score
2D Structure
EGF-06285
C27H21N3O5 | Exact mass: 467.1481
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
106
TPSA
468
MW
2
HBD
4.2
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight467.50 Da
TPSA106.1 A^2
HBD2
HBA6
SlogP4.16
Fsp30.037
Rotatable Bonds6
Rings4 (4 aromatic)
QED0.146
SA Score2.18 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC27H21N3O5
Exact Mass467.1481
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes