EGF-06368 Red

CCn1c(C(=O)NCC(=O)O)ccc1C(=O)NCC(N)CCc1ccccc1
0.259
Platform Score
2D Structure
EGF-06368
C20H26N4O4 | Exact mass: 386.1954
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
126
TPSA
386
MW
4
HBD
1.0
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight386.50 Da
TPSA126.5 A^2
HBD4
HBA5
SlogP1.01
Fsp30.350
Rotatable Bonds10
Rings2 (2 aromatic)
QED0.485
SA Score2.91 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC20H26N4O4
Exact Mass386.1954
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes