EGF-06370 Red

COC(=O)C1=C(c2ccc(F)cc2F)CC2CCC1N2C(=O)NCC1CCCCC1
0.344
Platform Score
2D Structure
EGF-06370
C23H28F2N2O3 | Exact mass: 418.2068
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
59
TPSA
418
MW
1
HBD
4.4
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight418.50 Da
TPSA58.6 A^2
HBD1
HBA3
SlogP4.42
Fsp30.565
Rotatable Bonds4
Rings4 (1 aromatic)
QED0.737
SA Score4.04 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC23H28F2N2O3
Exact Mass418.2068
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes