EGF-06404 Red

Cc1ccc(C2c3c(c(O)n(-c4ccc(Cl)cc4)c3O)ON2c2ccccc2)cn1
0.284
Platform Score
2D Structure
EGF-06404
C23H18ClN3O3 | Exact mass: 419.1037
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
71
TPSA
420
MW
2
HBD
5.2
SlogP
Display Controls
Rotate: drag | Zoom: scroll | Pan: right-drag | Double-click: center Loading...
EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight419.90 Da
TPSA70.8 A^2
HBD2
HBA6
SlogP5.15
Fsp30.087
Rotatable Bonds3
Rings5 (4 aromatic)
QED0.480
SA Score3.29 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC23H18ClN3O3
Exact Mass419.1037
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes