EGF-06508 Red

CC(c1cc(-c2ccccc2)no1)n1ccn(S(=O)(=O)c2ccc(Cl)c(Cl)c2)c1=O
0.284
Platform Score
2D Structure
EGF-06508
C20H15Cl2N3O4S | Exact mass: 463.016
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
87
TPSA
464
MW
0
HBD
4.5
SlogP
Display Controls
Rotate: drag | Zoom: scroll | Pan: right-drag | Double-click: center Loading...
EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight464.30 Da
TPSA87.1 A^2
HBD0
HBA7
SlogP4.46
Fsp30.100
Rotatable Bonds5
Rings4 (4 aromatic)
QED0.435
SA Score3.17 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC20H15Cl2N3O4S
Exact Mass463.016
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes