EGF-06542 Red

COc1cc(C2c3cc4c(cc3C(Nc3cc(F)ccc3F)C3COC(=O)C23)OCO4)cc(O)c1O
0.242
Platform Score
2D Structure
EGF-06542
C26H21F2NO7 | Exact mass: 497.1286
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
106
TPSA
498
MW
3
HBD
4.2
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight497.50 Da
TPSA106.5 A^2
HBD3
HBA8
SlogP4.20
Fsp30.269
Rotatable Bonds4
Rings6 (3 aromatic)
QED0.364
SA Score3.99 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC26H21F2NO7
Exact Mass497.1286
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes